Antibiotic-resistant biofilm is a complex microbial community associated in the high risk of morbidity and mortality of hospitalized patients. The current study aims to determine the antibiofilm activity of invasive Erigeron floribundus plant extracts often known as "abas-abas" against Staphylococcus… More

Antibiotic-resistant biofilm is a complex microbial community associated in the high risk of morbidity and mortality of hospitalized patients. The current study aims to determine the antibiofilm activity of invasive Erigeron floribundus plant extracts often known as "abas-abas" against Staphylococcus aureus and Pseudomonas aeruginosa. Bacterial strains were grown in M1 medium supplemented with fructose and cultivated for 24 and 48 hours at 30°C. Higher % biofilm inhibition was observed in gram-positive bacteria Staphylococcus aureus in most of the solvent use in extraction. Qualitative phytochemical screening was also evaluated and revealed the presence of tannins, flavonoid, saponins, steroid and the absence of alkaloid. The existences of these phytochemicals in the plant could be used to generate synthetic medications as a source of precursors. Moreover, this study also reveals that E. floribundus extract had antibiofilm action against the isolated nosocomial bacteria, implying that it could be used as an alternative to prevent microbial biofilm development. Less

Synthesis of zinc oxide nanoparticles on their antimicrobial activity utilizing banana peelings could be a potential candidate to develop nano-formulated natural products as an alternative, efficient, inexpensive, and environmentally safe method with specified properties. The study aimed to investigate the… More

Synthesis of zinc oxide nanoparticles on their antimicrobial activity utilizing banana peelings could be a potential candidate to develop nano-formulated natural products as an alternative, efficient, inexpensive, and environmentally safe method with specified properties. The study aimed to investigate the biological synthesis, characterization, and antimicrobial study of zinc oxide nanoparticles (ZnONps) against clinical pathogens Pseudomonas aeruginosa and Staphylococcus aureus using Musa acuminata × balbisiana peelings. Data revealed that varying concentration, temperature, and pH level can significantly influence the antimicrobial activity and plays crucial steps in the preparation of ZnONps. Research on nanoparticles as antibacterial agents can have an essential application in the food industry as antibacterial agents in food packaging and towards foodborne pathogens. Since this study deals with the preliminary investigation on banana peelings locally grown in the Philippines as capping and reducing agent through green chemistry, it can promote potential application in the Philippine food industry. By proper incorporation of nanoparticles into packaging materials it may inhibit or cause foodborne pathogens bacterial death. Less

Identification and subsequent isolation of anti-dengue active compounds in medicinal plants are potentially useful for developing antiviral chemical analogues. This study investigated the potential use of aqueous, methanolic, and ethanolic extracts of Syzygium sp. “O-on” against bacterial co-infection of Staphylococcus… More

Identification and subsequent isolation of anti-dengue active compounds in medicinal plants are potentially useful for developing antiviral chemical analogues. This study investigated the potential use of aqueous, methanolic, and ethanolic extracts of Syzygium sp. “O-on” against bacterial co-infection of Staphylococcus aureus and Pseudomonas aeruginosa in dengue. Taxonomic identification of Syzygium sp. “O-on” collected from Mindanao signifies possible new species through their distribution, ecology and conservation status. Phytochemical analysis showed that crude aqueous and organic solvent extracts contain medicinally important bioactive compound. Highest antimicrobial potentials were observed for the methanolic extracts of Syzygium sp. which inhibited 62.5 and 51.16% of the tested microorganisms, respectively, with higher activity against antibiotic-resistant bacteria (83.3%). We suggest that the Syzygium sp. could be potentially exploited to control the behaviors of this pathogen as well as for its utilization as a lead compound in screening for anti-dengue agents based on new antimicrobial targets. Less